FACT: Yes, epinephrine auto-injectors (e.g. EpiPen®, ALLERJECT®, EmeradeTM) can be given through clothing if necessary, but it’s best to avoid seams and pockets. The auto-injectors should be injected into the mid-outer thigh and you do not necessarily need to remove clothing to administer them.
Learn more
Treating reactions
Live demo by Dr. Julia Upton on using epinephrine auto-injectors
Mythbuster on recommended sites for epinephrine